Protein Details: Gap junction delta-4 protein

Protein ID

ICDB_Pro_1400

Protein Name

Gap junction delta-4 protein

Gene Name

GJD4; CX40.1

Organism

Homo sapiens (Human)

Length

370 amino acids

AlphaFoldDB

AF-Q96KN9-F1-model_v4.pdb

Function

Sequence

MEGVDLLGFLIITLNCNVTMVGKLWFVLTMLLRMLVIVLAGRPVYQDEQERFVCNTLQPGCANVCYDVFSPVSHLRFWLIQGVCVLLPSAVFSVYVLHRGATLAALGPRRCPDPREPASGQRRCPRPFGERGGLQVPDFSAGYIIHLLLRTLLEAAFGALHYFLFGFLAPKKFPCTRPPCTGVVDCYVSRPTEKSLLMLFLWAVSALSFLLGLADLVCSLRRRMRRRPGPPTSPSIRKQSGASGHAEGRRTDEEGGREEEGAPAPPGARAGGEGAGSPRRTSRVSGHTKIPDEDESEVTSSASEKLGRQPRGRPHREAAQDPRGSGSEEQPSAAPSRLAAPPSCSSLQPPDPPASSSGAPHLRARKSEWV

PDB Structures

8GN7 8GN8 8GNB

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Familial Cold Autoinflammatory Syndrome 2 and Familial Cold Autoinflammatory Syndrome

Location

Expressed in pancreas; kidney; skeletal muscle; liver; placenta; and heart

DOI ID

10.1515/bc.2002.076; 10.1093/dnares/12.2.117; 10.1038/nature02462; 10.1080/15419060302063; 10.1126/science.1133427

RefSeq

NP_699199.2